25 across
Unruly
lass,
nameless
one,
up
for
adoption
(8)
Unruly lass, nameless one, up for adoption (8)
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The definition is at the end of the clue.
How the clue works
The definition is adoption at the end, in the sense of taking up a cause. For the wordplay, "unruly" tells you to anagram three things: LASS, UP (straight from "up"), and "nameless one", which means taking the N out of ONE to leave OE. Shake LASS, UP and OE together and they rearrange into the answer.