Have a look at the bit in brackets, (One probably sits with a computer all day) — that's the definition, a cheeky way of describing the QWERTY keyboard, since that's what you're parked in front of all day at a desk. For the wordplay, Q is your standard abbreviation for 'Question', and then you need to shuffle the letters of 'weaker body Try' — 'exercising' is the anagram indicator telling you to do this — which rearranges neatly into WERTYKEYBOARD, giving you the rest of the answer once you stick the Q on the front.