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Killer
imprisoned
in
Windsor
Castle
(4)
Killer imprisoned in Windsor Castle (4)
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The definition is at the beginning of the clue.
How the clue works
See Killer at the start — that's your definition, pointing to a killer whale, an orca. Now look inside "windsOR CAstle" — "imprisoned in" is the hidden-word indicator, and if you read straight across those two words you find the answer lurking in plain sight.