12 across
Book
that
is
set
in
strange
land
(6)
Book that is set in strange land (6)
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The definition is at the beginning of the clue.
How the clue works
Nudge your glass over and look at Book — that's your definition, pointing to the Biblical Book of Daniel. "That is" gives you IE, and that gets tucked inside "strange" LAND, which is your anagram indicator sorting LAND into DAN...L around it — so you get DAN, then IE, then L, all strung together to spell it out.