17 across
Coarse
fabric
making
us
hurt
after
short
time
(7)
Coarse fabric making us hurt after short time (7)
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The definition is at the beginning of the clue.
How the clue works
Right, so "Coarse fabric" is what we're after — that's the definition, tussore being a rough kind of silk. For the wordplay: "short time" gets chopped down to just T, then you stick US straight after (that's "us" from the clue), and finish off with SORE for "hurt" — T, US, SORE all bolted together to give you the answer.