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Drugs
defence
involving
college
that’s
associated
with
Houdini
(10)
Drugs defence involving college that’s associated with Houdini (10)
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The definition is at the end of the clue.
How the clue works
The definition is associated with Houdini, the famous escape artist, giving escapology. Drugs give ES (ecstasy and speed), college gives C, and defence gives APOLOGY, which combine as ES + C + APOLOGY = ESCAPOLOGY.