23 down
Make
editor
ultimately
responsible
for
such
columns
(5)
Make editor ultimately responsible for such columns (5)
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The definition is at the end of the clue.
How the clue works
Right, so such columns at the end is your definition — that's pointing to the Doric order in architecture. For the build-up: "Make" gives you DO, then take the last letter, "ultimately", of "editor" which is R, and finally IC is your abbreviation for "in charge", i.e. responsible. Stick DO, R and IC together and you're at the columns.