16 down
Three
vitamins
removed
from
balanced
diet,
unwise
fix-up
(5,4)
Three vitamins removed from balanced diet, unwise fix-up (5,4)
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The definition is at the end of the clue.
How the clue works
Look at fix-up — that's your definition, a romantic meeting arranged by someone else. Take the letters of balanced diet, cross out the three vitamins A, C, and E, and then unwise tells you to anagram what's left to get your answer.