24 down
Bottom
part
of
horrid
android’s
turned
up
(5)
Bottom part of horrid android’s turned up (5)
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The definition is at the beginning of the clue.
How the clue works
Look at Bottom — that's your definition, meaning the lowest point. The answer is hidden inside "horrid android's", and "turned up" tells you to read those hidden letters in reverse, so working backwards through "rid and" gives you NADIR.