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Work
on
academic
cancelling
of
tyrant
(9)
Work on academic cancelling of tyrant (9)
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The definition is at the end of the clue.
How the clue works
Look at tyrant at the end — that's what you're after. You take OP for work, then PROFESSOR (academic) but with OF taken out ("cancelling of"), leaving you with PRESSOR. Stick OP in front of PRESSOR and there's your answer.