8 down
Somehow
heads
across
city’s
east
side
with
many
cycling
(2,3,5)
Somehow heads across city’s east side with many cycling (2,3,5)
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The definition is at the beginning of the clue.
How the clue works
Somehow is the definition. BEANS is slang for heads, and it goes round a filling made of Y (the east side, i.e. last letter, of city) plus MANY cycled round to ANYM — so B(YANYM)EANS gives BY ANY MEANS.