18 across
Promotes
risk
of
unprotected
sex
in
one
library
in
Edinburgh
(7)
Promotes risk of unprotected sex in one library in Edinburgh (7)
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The definition is at the beginning of the clue.
How the clue works
The definition is Promotes, in the sense of fostering or instilling something. Take I for one, then slot STI (sexually transmitted infection — your "risk of unprotected sex") inside NLS (the National Library of Scotland, "library in Edinburgh"), and you've got I + N(STI)LS.