25 across
Suddenly
discover
hotel
is
losing
pounds
(3,2)
Suddenly discover hotel is losing pounds (3,2)
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The definition is at the beginning of the clue.
How the clue works
The definition is Suddenly discover. Think of HILTON, your famous hotel, then drop the L (pounds, abbreviation) and you're left with HITON — or rather, HIT ON when you split it across those two words.