12 across
One
in
five
heading
to
Open
are
seeds
(6)
One in five heading to Open are seeds (6)
hints
0
checks
0
hints
The definition is at the end of the clue.
How the clue works
Look at seeds at the end — that's what quinoa is, of course, an edible grain. For the wordplay, you're building it up in pieces: one in five gives you QUIN (as in a quintuplet), then heading to Open means just the first letter, O, and finally are is abbreviated to A as a unit of area.