12 across
Vicious
swine
sent
back
in
time
machine
(6)
Vicious swine sent back in time machine (6)
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The definition is at the end of the clue.
How the clue works
The time machine from Doctor Who comes from stitching together SID (as in punk rocker Sid Vicious) and RAT (a swine, in the sense of a contemptible person), then turning the lot around — "sent back" — so SIDRAT becomes TARDIS.