24 down
Making
of
a
good
joke?
Turning
it
up
on
Dynasty
(6)
Making of a good joke? Turning it up on Dynasty (6)
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The definition is at the beginning of the clue.
How the clue works
The definition is Making of a good joke? — timing being the soul of comedy, as they say. For the wordplay, "turning it up" reverses it to give you TI, and then you stick MING on the end, that being a Chinese Dynasty.