16 down
Final
word,
effective
and
quite
open
(8)
Final word, effective and quite open (8)
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The definition is at the end of the clue.
How the clue works
Quite open is your definition — someone receptive or willing. Then it's a straight charade: AMEN is that "final word" (of a prayer), and ABLE means "effective", and you just stick them together.