2 down
Invigorating
air
in
Gozo?
Never!
(5)
Invigorating air in Gozo? Never! (5)
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The definition is at the beginning of the clue.
How the clue works
The definition is Invigorating air — that's your ozone, the stuff that gives seaside air that fresh, bracing quality. Then "in" is your hidden word indicator, and if you look inside "Gozo? Never!" you'll find the answer sitting right there.