21 across
Trousers,
lost
at
the
start,
eventually
turned
up
(9)
Trousers, lost at the start, eventually turned up (9)
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The definition is at the end of the clue.
How the clue works
"Lost" signals an anagram of "trousers", giving RETROUSS, followed by the start of "eventually", namely E. Together they make RETROUSSE, meaning turned up (as in a nose).