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Supplier
of
drug
mostly
impounded,
destroyed
(5,3)
Supplier of drug mostly impounded, destroyed (5,3)
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The definition is at the beginning of the clue.
How the clue works
The definition is Supplier of drug, pointing to OPIUM DEN. The wordplay takes "impounded" and removes the last letter thanks to "mostly", giving IMPOUNDE. Then "destroyed" is the anagram indicator, telling us to rearrange the letters of IMPOUNDE to get OPIUM DEN.