29 across
Cause
trouble,
as
Adam
and
Eve
did?
(5,4)
Cause trouble, as Adam and Eve did? (5,4)
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The definition is at the beginning of the clue.
How the clue works
This is a double definition. Cause trouble gives RAISE CAIN, which is an idiom meaning to create a disturbance or make a fuss. The second definition, as Adam and Eve did?, is a witty biblical reference — Adam and Eve literally raised (brought up) their son Cain, making it a playful double meaning.