20 down
Repudiate
key
source
of
hope
we
elevated
(6)
Repudiate key source of hope we elevated (6)
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The definition is at the beginning of the clue.
How the clue works
The definition is Repudiate — to reject or shun. You've got key giving you ESC (the Escape key on your keyboard), then source of hope giving the first letter H, and finally we elevated means "we" reversed, which gives you EW.