12 across
A
selfish
desire?
No
argument
there!
(6)
A selfish desire? No argument there! (6)
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The definition is at the end of the clue.
How the clue works
The definition is No argument there! — it's an expression of total consensus. Then the wordplay just strings together A and a selfish desire (greed), and A plus GREED gives you your six letters straight off.