16 down
Put
out
needing
two
days
to
cross
river
(6)
Put out needing two days to cross river (6)
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The definition is at the beginning of the clue.
How the clue works
The definition is Put out, meaning extinguished. You've got two days giving you two D's (the abbreviation for day), and those bracket river OUSE in the middle — D-OUSE-D.