11 across
European
town
beset
by
germs
spread
by
couriers
(10)
European town beset by germs spread by couriers (10)
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The definition is at the end of the clue.
How the clue works
The definition is couriers, giving you MESSENGERS. "Spread" tells you to anagram germs (giving you MGERS, if you like), then European town ESSEN gets "beset by" those scattered letters — M on one side, GERS on the other — to build the whole thing.