13 down
Heart
palpitating
over
wife
in
bedroom,
tickler
of
infant’s
bottom?
(10)
Heart palpitating over wife in bedroom, tickler of infant’s bottom? (10)
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The definition is at the end of the clue.
How the clue works
The definition here is tickler of infant's bottom, which rather vividly describes a parasitic worm known for causing itching in children. For the wordplay, 'palpitating' tells you to rearrange HEART into THREA, and then you put W for 'wife' inside DORM for 'bedroom' to get DWORM — stick those together and you've got your answer.