6 down
Murderer
in
good
book
residing
in
Jamaica
Inn
(4)
Murderer in good book residing in Jamaica Inn (4)
hints
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checks
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hints
The definition is at the beginning of the clue.
How the clue works
The definition is Murderer in good book — Cain being the biblical killer from Genesis. It's hiding right there inside "JamaiCA INn", with "residing in" telling you to fish it out.